Most left-handers find it natural to hold a guitar so they can strum the strings with their left hand and finger the chords with their right. If a standard right-handed guitar is just turned over the other way, all the strings are upside down, with the lowest notes at the bottom instead of the top. Some lefties have played this way, including Coco Montoya and Albert King but it is not ideal!
It is possible to re-string the guitar to change the string positions, and again many famous guitarists have played his way, notably Jimi Hendrix with his famous restrung Fender Stratocaster, but it is not really a great solution as the rest of the guitar is still in the wrong places – the direction of the string bridge, the protective panels, electric pickups, sound controls, cable jack, strap connections etc.
What you really need is a properly designed left-handed guitar with all the components made to be played left-handed. We are currently working with top guitar suppliers and distributors to bring you a wide selection of good left-handed guitars. Come check us back for updates!
Paul McCartney